The enigmatic Dr. Helen Magnus(AMANDA TAPPING) recruits an insightful forensic psychiatrist Will Zimmerman(ROBIN DUNNE) to join her in the quest to track, study and protect the strange, and often terrifying creatures that secretly populate our world.
An investigation into a string of bizarre robberies leads Magnus(AMANDA TAPPING) and Will(ROBIN DUNNE) to a crime ring of thieves who seem to be able to slip between the cracks of the law…literally.
Returning with an abnormal captured in the Himalayas, Magnus(AMANDA TAPPING) and Will(ROBIN DUNNE) are stranded from civilization and aid after their plane goes down in a desolate mountain range. While anxiously waiting for a rescue team, the surviving passengers begin to fall victim to vicious and deadly attacks throughout the night. It becomes chillingly apparent that surviving the cold is the least of their worries and no one, not even Magnus and Will, is above suspicion.
When a mating pair of cute, furry and seemingly harmless abnormals is brought in for scientific study, the Sanctuary team begins to exhibit some hidden animal attractions for one another.
While leading a covert meeting in Rome, Magnus encounters an old friend from her past who confides that the Cabal has come to exact revenge on her for the events in "Fata Morgana".
A young artist with an uncanny ability to draw remarkably detailed pictures from memory may be the key to solving a case surrounding the suspicious death of his abusive father.
Investigating the disappearance of an old college friend, Will(ROBIN DUNNE) finds himself caught in an underground fight club where the combatants are genetically engineered abnormals who fight to the death like modern day gladiators.
The Five, led by Magnus, attempt to find the secret labyrinth in the decimated city of Bhalasaam. Once located, they must complete a series of cryptic tests that can only be achieved using each of their unique powers.
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