The Chihuahuan Desert is a desert that spans over a wide portion of the Southwestern region of the United States and across the border down into the country of Mexico.[2] It is referred to non-specifically on Sanctuary as the "New Mexican desert".
Albuquerque is the largest city located within the state of New Mexico.[3]
Episode 2x03 - "Eulogy": After suffering the believed loss of her daughter Ashley Magnus, Helen Magnus starts to have old memories resurface. In a flashback set during 1957, Magnus was traversing the New Mexican desert within the Navajo Nation near Albuquerque in search of a 'nonexistent' place called Tehuatonichen. On the passenger seat of her vehicle, a copy of the Albuquerque Daily newspaper is seen.
One hundred miles south of Santa Fe is Albuquerque. The driving distance between the city centers of Santa Fe and Juárez is an average of about 328 miles, placing Virgil's lab roughly 228 miles directly north of where the psych worm surfaced.
Holloman Air Force Base is a military base located just outside of the city of Alamogordo.[6]
Episode 4x05 - "Resistance": During the teaser sequence of the episode, SCIU usurps the Captured Abnormal from the Old City Sanctuary team. According to the GPS data Henry Foss reviews from their hidden tracking beacon, the abnormal was airlifted across the U.S.-Canada border to Holloman Air Force Base which is located just outside of the city of Alamogordo. From there, the abnormal was transported to Area 51 located in the middle of the New Mexican desert.